Monte Carlo dose calculation for advanced radiotherapy treatments

 

C-M Charlie Ma, Ph.D.

Professor and Director, Radiation Physics

Department of Radiation Oncology

For Chase Cancer Center

Philadelphia, PA 19111, USA

 

The Monte Carlo method is a statistical simulation method. For radiation transport problems, it simulates the tracks of individual particles by sampling appropriate quantities from the probability distributions governing the individual physical processes using machine-generated random numbers. Average values of macroscopic quantities such as particle fluence, energy spectrum and absorbed dose distribution can be calculated by simulating a large number of particle histories. It is widely accepted that the Monte Carlo technique is the most accurate method for dose calculation, which is capable, in principle, of accurately computing the dose under almost all circumstances.

 

This lecture will briefly describe the principles and the implementation of the Monte Carlo method and review its applications in radiotherapy with a focus on the recent developments in dosimeter response studies, medical accelerator simulations and its use for dose calculation in treatment planning and dosimetry verification for advanced radiotherapy treatments. The educational objectives are: (1) to understand the principles and implementation of the Monte Carlo method and (2) to review the applications of the Monte Carlo method in radiation therapy with a focus on detector response studies, accelerator simulations and treatment planning dose calculation and beam delivery verification.