TA25a-Stereotactic Radiosurgery/Radiotherapy, Linac, CyberKnife

(Yin/Yu)  3HT2-TA25

Fang-Fang Yin, Ph.D.

Stereotactic radiosurgery (SRS) of an intracranial lesion, or radiosurgery, combines the use of a stereotactic apparatus and energetic radiation beams to irradiate the lesion with a single treatment. Stereotactic body radiosurgery (SBRS) of a lesion outside of the brain combines the use of a stereotactic apparatus and energetic radiation beams to irradiate the lesion with a single treatment. Stereotactic Radiotherapy (SRT) utilizes the stereotactic apparatus and radiation beams for multiple fractions or treatments. The key steps for SRS/SRT involve (1) Accurately define the shape and location of the lesion and critical normal structures/organs in the reference frame of a stereotactic frame system with CT, MRI or angiography, etc. and incorporate information from other anatomical/functional images; and (2) Develop and deliver the planned treatment.  The treatment techniques produce a concentrated dose in the lesion with steep dose gradients external to the treatment volume. The rapid dose falloff from the edge of the treatment volume provides dramatic sparing of normal brain tissues. In this lecture, advanced technologies such as image-guided frameless and intensity-modulated methods will be described for SRS/SRT. Specific discussions will involve how these techniques could be effectively implemented in the each step of treatment procedures such as immobilization, simulation, treatment planning, target localization, delivery, and verification.

TA25a-立体定向放射手术/放射治疗、加速器、赛博刀

(Yin/Yu)  3HT2-TA25

Fang-Fang Yin, Ph.D.

颅内病变的立体定向放射手术（SRS）或放射外科结合立体定向装置和高能放射线束在一次治疗中照射病变。脑外病变的立体定向体部放射手术（SBRS）结合立体定向装置和高能放射线束在一次治疗中照射病变。立体定向放射治疗（SRT）利用立体定向装置和放射线束分多次进行治疗。SRS/SRT的关键步骤包括(1)在以CT、MRI或血管造影等立体框架系统为基础的框架上，参考其他解剖/功能影像的信息，精确的定义病变和重要正常结构/器官的形状和位置；(2)制作并实施计划的治疗。治疗技术将剂量集中在病变的同时，在治疗区域的外部产生了陡峭的剂量梯度。治疗区域边缘剂量的迅速跌落为正常脑组织提供了非常好的保护。本讲将介绍用于SRS/SRT的图像引导的无框架调强方法，还要讨论这些技术怎样才能够被有效的贯彻到治疗过程中的每一步，如定位，模拟，治疗计划，靶区定义，实施和验证。