4C03-Image-Guided Radiation Therapy

Fang-Fang  Yin, PhD

Radiation Oncology

Henry Ford Hospital System

Dept of Radiation Oncology

Detroit, MI  48202

The primary purpose of radiation therapy is to delivery expected high dose to tumor volume while limiting radiation damage to normal organs/structures within tolerances. For the last several years, the rapid development of intensity-modulated radiation therapy techniques enables radiation therapy to delivery high radiation doses shaped to the treatment tumor volume. The current challenge is how to ensure the tumor volume is accurately identified as planned and the radiation dose is accurately delivered to the treatment volume as prescribed. Image-guided radiation therapy is emerging to be a critical direction for radiation therapy. In this talk, various image-guided techniques will be discussed to improve the accuracy of radiation therapy. Specific discussions will includes multi-modality imaging methods (anatomical, functional, and molecular imaging methods) for tumor identification, kV, MV and ultrasound imaging methods in the treatment room for patient setup, target localization, and treatment verification. With the image-guided techniques, cancer treatment is capable of including 4-dimentional information, i.e., the management of organ motion to minimize treatment margin added to the clinical target volume. Applications of image-guided techniques in conventional radiation therapy, intensity-modulated radiation therapy, stereotactic brain and body radiosurgery and hypo-fractionation radiotherapy, and 4-D simulation to verification will be discussed.

4C03－图像引导的放射治疗

Fang-Fang  Yin, PhD

Radiation Oncology

Henry Ford Hospital System

Dept of Radiation Oncology

Detroit, MI  48202

放射治疗的主要目的是给予肿瘤区域高剂量，同时将正常器官/结构的辐射损伤限制在可以耐受的范围内。在过去的几年里，调强放射治疗技术的快速发展可以使高剂量区与肿瘤区域高度适形。目前的主要挑战是如何保证被照范围是计划预定的肿瘤区域，以及如何保证将处方剂量准确地给予到预定的治疗区域。图像引导的放射治疗是放射治疗一个非常重要的发展方向。本报告将讨论改善放射治疗准确性的几种图像引导技术，具体内容包括用于确定肿瘤范围的多种成像方法（解剖成像、功能成像和分子成像）和治疗室中用于病人摆位、靶区定位和治疗验证的kV、MV和超声成像技术。使用图像引导技术，肿瘤治疗可以包含四维信息，即通过考虑器官运动来最小化临床靶区周围外放的边界（margin）。本报告将讨论图像引导技术在常规放射治疗、调强放射治疗、脑部和体部立体定向放射外科和大剂量分割放射治疗中的应用，最后讨论一下四维模拟和验证技术。